One of the most difficult and least discussed issues amongst women past childbearing years is our sexual health. Vaginal atrophy, while normal, can be disruptive to a satisfying sexual relationship. Vaginal dryness, pain, and volume loss due to reduced estrogen does not mean that women should simply tolerate these physical challenges and changes.

Our special, 15-minute treatment can help restore volume, reduce or eliminate irritation, improve natural lubrication, and enhance the orgasm experience by improving sensitivity to stimulation. Although some patients notice the effect almost immediately, it can take up to 3-4 weeks for others to achieve the full rejuvenating effect. Another benefit of the improved tissue health and volume of the vaginal area is the elimination of stress incontinence. This improvement is immediate for most patients.

Does the O-Shot hurt?

The injection site is treated with a topical anesthetic so the patient feels pressure, but typically no pain. There is no downtime with the injection, although there may be some discharge immediately following the procedure.

Can I drive home after an O-Shot treatment?

Yes. Injections are performed under local anesthesia and there is no post-treatment waiting period, and patients are ready to go home immediately.

Julie Holesh, PA

Physician assistant Julie Holesh is board-certified by the National Commission on Certification of Physician Assistants. With both an artistic eye and medical expertise, she can help you achieve optimal skin quality with injectables, laser treatments, and other med spa services.

Julie Holesh, PA-C

How quickly can I expect O-Shot injection to work?

It varies with each patient. Some feel improvements immediately, for others, it may take up to 3-4 weeks to feel the full effect.

  • Enhanced Sensitivity: The O-Shot improves sexual responsiveness and increases sensitivity in the vaginal and clitoral areas, enhancing sexual pleasure and orgasm intensity.
  • Urinary Incontinence Improvement: It aids in the reduction of urinary incontinence, providing better urinary control and improving overall quality of life.
  • Increased Lubrication: Women experiencing vaginal dryness can benefit from increased natural lubrication, reducing discomfort during sexual activity.
  • Non-Surgical & Minimal Downtime: As a non-invasive treatment, the O-Shot requires no surgery and has minimal downtime, allowing women to quickly return to their daily activities.

Collagen: A protein that provides structure to much of your body, including your skin, hair, and nails. 

Vaginal Rejuvenation: A general term for procedures that aim to improve the aesthetic or functional aspects of the vagina, often associated with the O-Shot.

Urinary Incontinence: A condition that the O-Shot may help alleviate, characterized by the loss of bladder control.

Libido: Refers to sexual desire, which some patients report increases after receiving the O-Shot.

Dyspareunia: A term for painful intercourse, a symptom that the O-Shot may help mitigate.

Autologous: Referring to the derivation of tissues or cells from the same individual to be used during a treatment or procedure.

Does the O-Shot really help with urinary incontinence?

Yes! Urinary incontinence caused by childbearing and/or age is frustrating for so many women. The effect of the O-G injection is immediate for most and involuntary leakage.

Does the O-Shot help improve vaginal dryness?

Yes, the O-Shot can often eliminate the need for over-the-counter lubricants, because you naturally produce vaginal secretions.

“I had the O-G Injection at Claytor Noone Plastic Surgery in May of 2019. There were many reasons for me choosing to have it done: “leaking” when I cough, sneeze, laugh or exercise, but an added bonus was a better orgasm! The shot itself is pain-free, there is no downtime and the results for me were immediate. I’d say it was a win-win!”

—D, July 2019

How do I prepare for the blood draw?

Be sure to drink plenty of water before you come to the office to ensure you are sufficiently hydrated. 50% of your blood is made up of water, so being hydrated will make it easier for the nurse or technician to locate your veins and draw your blood.

Can I take my regular medications before getting the O-Shot?

Yes. Take your medications as you normally would.

How long does it take to heal from getting the O-Shot?

There should be little to no downtime due to the procedure.

How often do I need to have the injection to maintain the effect?

Results have shown the O-Shot injection to be effective for up to a year.

Are there any limiting factors to receiving the O-Shot?

Heavy smokers and those on blood thinners are not candidates for these injections.

Is the nurse or doctor who will be doing the injection certified for this procedure?

Yes. Both Dr. Claytor and our nurse are highly trained and certified injectors.

References »

Sukgen G, Ellibeş Kaya A, Karagün E, Çalışkan E. Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction. Turkish Journal Of Obstetrics And Gynecology. 2019 Dec;16(4):228-234. doi: 10.4274/tjod.galenos.2019.23356. 

Le C, Murgia RD, Noell C, Weiss M, Weiss R. Female genitourinary treatments in aesthetics. Clinics in Dermatology. 2022 May-Jun;40(3):259-264. doi: 10.1016/j.clindermatol.2021.11.009. 

Cohen PR, Riahi RR. Platelet-Rich Plasma and Genital Rejuvenation. Skinmed. 2019 Jul 1;17(4):272-274.

Prodromidou A, Zacharakis D, Athanasiou S, Protopapas A, Michala L, Kathopoulis N, Grigoriadis T. The Emerging Role on the Use of Platelet-Rich Plasma Products in the Management of Urogynaecological Disorders. Surgical Innovations. 2022 Feb;29(1):80-87. doi: 10.1177/15533506211014848.

Schedule a consultation

To learn more and determine whether the O-shot may be right for you, schedule a consultation by calling 610-527-4833 or contacting us online.

Areas served:

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Medically reviewed by Dr. R. Brannon Claytor — Updated on Feb 20, 2024